Sentence examples for substrates that include from inspiring English sources

Our results indicate that specific ECM substrates that include type IV Collagen, laminin and heparan sulfate support and maintain neuronal and glial differentiation to different extents.

Hymenoscyphus ericae is a major ericoid fungus that has been extensively investigated for its ability to grow on a variety of complex organic substrates that include carboxymethylcellulose (CMC) (Leake and Miles 1996).

ATM and ATR together with CHK1/CHK2 kinases phosphorylate a number of effector substrates that include BRCA1, Rad51, p53, and Mdm2 [28].

Certain classes of the large and diverse family of methyltransferases (I-III) have very diverse substrates that include amines, alcohols, carboxylic acids, thiols, sulfides, alkenes and alkanes [36], [37].

We argue this may be because the active site of an enzyme requires unusual properties with respect to the rest of the protein, for example, many active sites (including the current example provided here) comprise deeply protected clefts which may be required for interaction with substrates that include substantial hydrophobic patches.

The DPP1 - and LPP1 -encoded lipid phosphate phosphatase enzymes dephosphorylate a broad spectrum of substrates that include DAG pyrophosphate (DGPP), PA, lysoPA, sphingoid-base phosphates, and isoprenoid phosphates (Toke et al. 1998, 1999; Faulkner et al. 1999).

Instead, it preferred substrates that included a lysine mutation, consistent with reports that p300 prefers substrates with a distal lysine residue.

The authors suggest a possible role of CCD4a in berry colour, flavour and aroma of Chardonnay berries, even though functionality could not be demonstrated with a number of carotenoid substrates that included β-carotene and zeaxanthin [ 46].

Furthermore, the caveolin-1-mediated increases in AKT activity were sufficient to cause the sequential phosphorylation of multiple downstream AKT substrates that included GSK3, FKHR and MDM2 Lii et al, 2003).

It is not completely understood what determines which adenosine in a pre-mRNA molecule will be targeted for deamination in vivo, but essential prerequisites are secondary structures in the RNA substrate that include double-stranded components within the vicinity of the editing site on one hand, and the presence of an adenosine deaminase on the other.

Briefly, the kit consists of an ELISA-based activity assay that uses a 50-amino-acid GST-IκBα fusion-polypeptide substrate that includes the Ser32 and Ser36 IKK-2 phosphorylation sites.