Sentence examples for substrates target from inspiring English sources

Sensitizer-linked substrates target cytochromes P450 in a background of other heme enzymes, and their demonstrated biosensing and substrate screening capabilities may facilitate future drug design efforts.

Although these bacterial substrates target proteins that control host cell secretory traffic, most of the IDTS are dispensable for replication vacuole formation, indicating that there may be considerable functional redundancy in this system (Luo and Isberg, 2004).

Through a cascade of steps, c-Cbl then induces the ligation of ubiquitin molecules to its substrates, targeting them for internalization and degradation.

The Slx5 Slx8 complex is a ubiquitin ligase that preferentially ubiquitylates SUMOylated substrates, targeting them for proteolysis.

Are novel Map3k1 PHD motif substrates targeted by the Ub-proteasome system during apoptosis?

A biological molecule, e.g., an enzyme, tends to interact with its many cognate substrates, targets, or partners differentially.

Like ubiquitin, PUP is covalently attached to substrates targeted for degradation, but the sequences of the two proteins are not related to each other.

Ltn1 belongs to the RING domain family of E3 Ub ligases that ubiquitinate substrates targeted for degradation by the 26S proteasome (Deshaies and Joazeiro, 2009; Finley, 2009).

The use of these approaches does not always fully mimic the physiological conditions or encapsulate the full spectrum of substrates targeted by protein QC.

Relative specificity is defined as the characteristic whereby in a biochemical system, a molecule, symbolized as E, interacts with its numerous substrates, targets or partners (collectively symbolized as {S}) differentially, thereby impacting them distinctively depending on the identity of individual substrates, targets or partners [1].

First, fluorocarbon film was deposited on a substrate target polytetrafluoroethylene (PTFE) using RF sputtering.