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In addition, multi-specific or promiscuous enzymes exhibit activity toward a wide range of substrates so as to increase cell evolvability and robustness.
The development of models to predict p38 MAPK docking-domain specificities may permit the design of inhibitory peptides to block the phosphorylation of specific subsets of substrates so as to block specific pathways mediated by p38 MAPK [ 37]. p38 MAPK substrates can be divided into two categories, namely transcription factors and protein kinases (Table 1).
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The transporter must be able to undergo a conformational change when not bound to either substrate, so as to complete the cycle and return the binding sites to the side from which driving and driven substrates both move.
Different bond lengths were analysed in double shear bond tests, using clay brick walls as substrate, so as to evaluate the influence of the bond length depending on the reinforcement system used.
These developed properties could provide high geometric surface area for a catalytic γ-Al2O3 washcoat, and enhance the adhesive strength between ceramic washcoat and metal substrate so as to extend the lifetime of the washcoat.
Analysis was made with a non-fluorescing background plate placed under the verso paper substrate so as not to pick up elements from the next folio.
Analysis depth was in the region of 2 cm depending on the element, and therefore a non-fluorescing background plate was placed under the verso paper substrate so as not to pick up elements from the next painting in the volume.
In many plants enzymes are separated from their substrate so as to avoid reactions occurring when the plant is growing.
Thus, Ser-440 and −467 have not been identified as substrates so far.
The surface of this funnel is predominantly hydrophobic so as to allow access of fatty acid moieties of substrates.
He's looking forward to yet more development, "when we can have the thin films of today on a flexible substrate" rather than the present glass substrates, so that the TVs can be rolled up and tucked into a backpack.
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