Sentence examples for substrates serving as from inspiring English sources

However, less than 2%% of the human genome accounts for protein-coding transcripts, while a large portion of the genome expresses non-coding RNAs, implicated in multiple biological roles regulating gene expression, guiding epigenetic processes, sensing cellular substrates, serving as catalysts or enzymes, and supporting structural functions [ 4].

The cell substrates serve as the front window and present a tight seal.

Preheated mirror-polished stainless steel substrates served as a reference point for further comparison with rough, cold or bond-coated substrates.

The ITO substrates served as the working electrode, platinum worked as the counter electrode, and an Ag/AgCl electrode was the reference electrode.

Increasing evidence indicates that many marine sediments (stream substrates) serve as reservoir of pathogenic microorganisms of faecal origin (e.g. Escherichia and Enterococcus), including pathogenic and virulent strains of bacteria (Alm et al. 2003; Luna et al. 2010).

Proteases and their substrates serve as the nodes.

When the substrates served as nitrogen sources, the final nitrogen concentration was adjusted to 2.5 mM.

Quantitative analysis of radiolabelled P NAD+ hydrolysis in the presence of acetylated histone or peptide substrates has therefore been reported to provide a measure of the degree to which putative sirtuin substrates serve as deacetylation targets (Tanny and Moazed, 2001).

In yeast and mammalian cells, an exposed α1,6-mannose residue present on N-glycans of ERAD substrates serves as a signal for degradation and is recognized by YOS9 or its human orthologues OS-9/XTP3-B [ 14, 34, 35].

Our study demonstrating specificity in the binding of Pellinos to phosphorylated peptides and to intact substrates serves as encouragement that agents can be developed to specifically target an individual Pellino for pharmacologic intervention with minimal off-target effects.

However, the majority of these substrates serve as pharmacological targets in vitro, but few have been shown to be endogenous, physiological substrates (defined as peptides whose endogenous circulating level of intact versus N-terminally cleaved forms is altered after reduction or elimination of DPP4 activity in vivo) [ 44].