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The neural substrates responsible for semantic dysfunction during the early stages of AD have yet to be clearly identified.
However, as the total complement of prenylated proteins is unknown, the FTase substrates responsible for farnesyltransferase inhibitor efficacy are not yet understood.
Finally, it should be noted that, some previous studies have shown that migraineurs, in the intercritical phase and in the migraine attack, have abnormalities in the function of neural substrates, responsible for different stages of auditory processing [11, 13].
One recent study evaluated the possible relationship between migraine, during attacks, and auditory processing; the authors concluded that the function of the neural substrates, responsible for auditory processing information, is impaired during the migraine attack [25].
Furthermore, a recent study, showing a deficit in auditory processing during the migraine attack, reinforces this hypothesis, and the authors indicate that the function of neural substrates, responsible for different stages of auditory information processing, is impaired also during the acute migraine [25].
Yet, little is known about the substrates responsible for thermotolerance of the nervous system to stresses such as hyperthermia.
Similar(40)
We have identified the neuronal substrate responsible for the venom-induced manipulation of the cockroach's drive for walking.
We reasoned that a substrate responsible for the shared essential function of Ste20p and Cla4p might itself be essential.
As such, our present study aimed at employing the wasp-cockroach parasitic interaction to define the neural substrate responsible for the drive to initiate walking in insects.
For the first process, the existence of the direct motor pathway connecting the oro-facial motor cortex and the medullar phonatory and respiratory areas, including the nucleus ambiguus, has been suggested as an anatomical substrate responsible for vocal plasticity [3].
In order to examine further the anatomical and pharmacological substrate responsible for this high intraindividual variability disorder, we injected GABAA antagonist (bicuculline) or GABAA agonist (muscimol) in the dlPFC of monkeys performing a reflexive oculomotor task.
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