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The results showed that this additive has potential advantages in biochemical reactions of hydrophobic substrates, particularly for enantioselective biosynthesis.
Although FTase and GGTase-I are highly homologous, they are quite selective for their substrates, particularly for their isoprenoid diphosphate substrates, FPP and GGPP, respectively.
Analysis by GC showed significant increases in the amount of polymer produced by E. coli RSC02 when compared to E. coli LSBJ for nearly all fatty acid substrates, particularly for those with six or fewer carbons (Table 3).
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However, the EB-FRCM system is characterized by poor FRCM/concrete bond leading to premature debonding of FRCM off the concrete substrate, particularly for thicker FRCM.
We found that ERAP1 exhibited very strong preferences for specific amino acids in several positions of the peptide substrate, particularly for hydrophobic and positively charged side-chains.
Soon after calving in high-yielding dairy cows, nutritional and energetic demands can increase 4-fold within a single day as the animal undergoes a physiological upheaval to meet the demand by the mammary gland for substrates, particularly glucose, for milk production.
These amino acid alterations are known to affect the activities of the resultant GSTZ1 enzyme for different substrates, particularly dichloroacetates and fluroacetates, affecting the efficiency of removal for these substances.
Perturbation of the salt bridges upon substrate binding has been also reported for the mitochondrial ADP/ATP carrier (AAC), suggesting a general mechanistic element for how substrate binding, particularly for charged substrates, might facilitate the progression of larger-scale conformational changes.
Formation of polyubiquitin chains on substrates, particularly chains where the C-terminus of the distal ubiquitin moiety is linked to lysine 48 of the more proximal ubiquitin moiety, targets the substrate for recognition and degradation by the proteasome.
A similar approach, called MA-Chord [31], is a DHT substrate particularly designed for mobile ad hoc networks that combines AODV routing and Chord overlay routing at the network layer to provide efficient key-based routing in MANETs.
Absence of phenotypes may be explained either by redundant substrate specificities (particularly for subfamily C transporters), non-essential functions, or specific functions at developmental stages that were not assessed by larval injections.
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