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We now know that PfSUB1 has multiple physiological substrates, most of which are cleaved at more than one site.
Although these different models have been applied to different substrates, most of these mechanistic models fit into two- and three-parameter mechanistic models.
The metabolic rate of an organism is the total sum of all energetic transformations occurring in its body and depends on the supply of substrates, most of which come in the form of food as described by the functional response.
P-gp has numerous substrates, most of which are lipophilic, including antiepileptic drugs (phenobarbital, carbamazepine, phenytoin, and lamotrigine), antitumor drugs, immunosuppressants, adrenocortical hormone, analgesics, cytokines, histamines, calcium channel blockers, cardiac glycosides, antidepressant drugs, and antibiotics (Table 1) [ 8].
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Polymers provide the coating film its capacity to adhere to the substrate, most of its chemical resistance, and flexibility.
By pasteurization of substrate, most of contaminating microorganisms are killed and protein can be utilized by growing mushroom.
With the Ga source at a distance of 15 cm to the substrate, most of the nanowires grown were not vertically aligned to the substrate, as shown by the cross-sectional and top-view images in Figures 3a,b, respectively.
Additionally, with 1 h as a substrate, most of the ene reductase activity (Table 3, entries 7 9) was retained in the cell-free extract, whereas only minor activity was still detectable in the cell pellets.
When pyruvate + proline is used as substrate most of the ROS generated are directed to the mitochondrial matrix where dj-1β can exert its detoxifying action, whereas when SP3G is used as the substrate ROS production is split between the matrix and the inter-membrane space [ 31], decreasing the potential role of dj-1β in the detoxification process.
Specimens (58 individuals) are commonly found attached to a variety of substrates, most commonly (32 out of 58 individuals) on the spicules of the sponge Pirania but also on Tubulella and on other individuals of M. burgessensis.
For some of the substrates (most notably 12-pNCA and 2PE), many of the P450 variants were sufficiently active to either saturate the substrate or exceed the linear range of absorbance readings.
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