Sentence examples for substrates may help from inspiring English sources
This novel pattern of substrate homology between cytoplasmic SIRT1 and mitochondrial SIRT3 suggests that considering evolutionary relationships between the sirtuins and their substrates may help to identify and understand the functions and interactions of this gene family.
This research paves the way towards controllable growth of the silicide NWs on silicon substrates, which may help to advance the realization of practical applications of silicide NWs in nanoelectronics.
Further experiments will elucidate the signaling pathways that enable (or inhibit) growth on soft substrates, which may help tailor treatments for tumors based on the mechanical milieu in which they thrive.
This is critical for maintaining the correct orientation of the substrate and may help stabilize the oxazoline ion intermediate during substrate assisted catalysis.
Hence, enhanced TCA-cycle mediated substrate-level phosphorylation may help signal a dysfunctional Fe-metabolism and evoke a response reminiscent of anaerobiosis [39].
The inhibitor appears to mimic the substrate transition state, which may help explain the potency of this inhibitor and the catalytic mechanism of pyrimidine nucleotide phosphorylases (PYNPs).
Why the introduction of a polar amino acid at this position would improve the efflux of hydrophobic compound is unclear, but every substrate must eventually leave the binding site in order for its efflux to occur, so the substitution A279T (hydrophobic to polar residue) may help substrate release to the gate and the funnel.
In addition, the demonstration of differences in MRI signal intensity in non-compacted myocardium may help identify substrates for potentially lethal arrhythmias [34].
In this context, Derlin-1 works in concert with p97 and, because of its rhomboid architecture, by compressing and deforming the lipid bilayer, may help ERAD substrates crossing the membrane (29).
Thus, understanding the potential substrate specificity of pol ν may help to guide future investigations of its biological role in TLS and circumstances for induction or activation.
