Sentence examples for substrates may contribute from inspiring English sources
Studies suggest that the physiological changes of pregnancy, designed to increase maternal energetic efficiency and liberate fetal substrates, may contribute to a worsening of obesity in susceptible subjects.
One category of caspase substrates may contribute to specific morphological features of this mode of cell death.
These observations indicate that PS acting by a presynaptic mechanism regulate glutamatergic neurotransmitter release and LTP induction and suggest that impaired proteolysis of PS substrates may contribute to the synaptic defects caused by loss of PS function.
The impairment in degradation of autophagic substrates may contribute to several aspects of NPC neuropathology, including the accumulation of ubiquitinated proteins and the generation of reactive oxygen species.
This supports the concept that alternative/additional mechanisms and anatomic substrates may contribute to the induction/perpetuation of autoimmune responses during the pathologic history of RA [ 10, 82, 83].
Several factors related to a higher CrI of the substrate may contribute to the reduction of digestibility at the lower enzymatic loading: the decrease in the reactivity of the substrate during hydrolysis; different kinds of enzyme inactivation; and non-specific adsorption of enzymes onto lignin [ 30].
It has a number of downstream substrates that may contribute to tumor genesis.
AKT is the primary mediator of PI3K-initiated signaling and has a number of downstream substrates that may contribute to malignant transformation.
On the other hand, the obese/T2DM heart is less capable of switching between circulating substrates, which may contribute to a reduced intrinsic protective capacity.
Metabolome analyses have uncovered many secondary metabolites that appear to be species specific and it has been suggested that broad substrate specificity may contribute to metabolome diversity [16].
Taken together these results indicate that RTP801 is a novel parkin substrate that may contribute to neurodegeneration caused by loss of parkin expression or activity.
