Sentence examples for substrates in its from inspiring English sources

The architecture of Skp is unexpectedly similar to that of Prefoldin/GimC, a cytosolic chaperone present in eukaria and archea, that binds unfolded substrates in its central cavity.

These findings suggest that A. fumigatus is able to detect different complex proteins available as substrates in its environment and regulate protease secretion accordingly.

This variant is more likely to trap non native substrates in its central channel, and the extra density seen in this complex is likely to arise from denatured protein, possibly ClpP, present in the sample.

The amino acid sequence diversity of the predicted acyl-CoA synthetases might indicate different substrate specificities of these enzymes, which would enable C. variabile to utilize a broader range of fatty acid substrates in its natural cheese habitat, probably leading to a growth advantage as a well-adapted species.

Casein kinase II is also known to use ATP and GTP as co-substrates in its reaction [ 31] and it has been shown recently that the majority of phosphorylation events in the chloroplast stroma fall into this category [ 14].

The results clearly indicate the occurrence of heteroepitaxy of PBA on the iPP substrate in its β-form with both molecular chains ±50° apart from.

Epitaxial growth of the perfectly alternating ethylene carbon monoxide copolymer (POK) has been successfully achieved using hydroquinone, first as a solvent in its liquid state, and then as a substrate in its crystallized form.

The phosphate moiety rapidly associates with R45 in the apex whose guanidinium group acts like a "fork" stabilizing the substrate in its binding site.

Binding of substrate lowers the free energy depending on the strength of the bonds formed, which in turn depends on the precise geometry of the substrate in its binding site (lower black lines, Fig. 6).

Overall, this analysis of the structural ensembles of human lysozyme suggests that, as a consequence of a concerted conformational transition, the enzyme explores conformations in which the specific and tight intermolecular interactions with the substrate in its locked state are largely lost in favour of the formation of weak and non-specific interactions in its unlocked state.

Motivated by the close homology between Rnl2 and TbREL1 and the desire to understand the functional dynamics of the kinetoplastid ligation reaction, we investigate the conformational dynamics of TbREL1 in complex with a nicked dsRNA substrate in its canonical A-form.