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These properties coupled with the fact that ABPs can be used to biochemically monitor protease targets after imaging make them preferential to substrates for some imaging applications.
Einstein's brain has an extraordinary prefrontal cortex, which may have contributed to the neurological substrates for some of his remarkable cognitive abilities.
Most essential AAs are neutral, with long or bulky chains and are substrates for some of the system-L amino acid transporters (LAT) [ 96].
In a few cases it is possible that more than one peptidase is involved in processing, or there may not be enough known substrates for some peptidases to be sure that an atypical replacement is really unacceptable.
It has been demonstrated that inversions to the reference AZFc sequence are required as substrates for some deletions (Fernandes et al., 2004; Repping et al., 2004), still it is currently unknown whether they can actually increase the likelihood of subsequent rearrangements.
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GaSb is also an ideal substrate for some longer wavelength lasers and photodetectors [3 5], low-power-consumption electronic devices [6], optoelectronic devices with varying wavelengths [7] and ordered semiconductor quantum dots [8].
Which of these processes is the rate-limiting step in the overall proteolysis reaction depends on the specific substrate; for some proteins, the unfolding process is rate-limiting, while deubiquitination is the slowest step for other proteins.
Since tyrosine phosphorylation is one of the first steps in growth factor receptor signaling activated in tumorigenesis [44], our findings raise possibilities that NFIX could be a substrate for some oncogenic growth factor such as PDGFB, with which it has been shown to cooperate in glioma formation.
While bacteria are required for metabolism of some ginsenosides, it is also possible that ginseng might alter the microbial flora since it is a substrate for some bacteria.
Although, in retrospect, the discovery of d-gluconate as a substrate for some members is not surprising because d-gluconate and d-mannonate are epimers at carbon-2 so they yield the same dehydration product, this stereochemical difference requires that a base other than the Tyr-Arg dyad in the "150 180s" loop abstract the 2-proton from d-gluconate.
Results of last investigations showed that coco peat and perlite were sufficient substrates for growing of some plants especially for vegetables and grower use this materials as growing media in greenhouse cultures.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com