Sentence examples for substrates for numerous from inspiring English sources
Histones are the primary compaction units of DNA and are the substrates for numerous PTMs including acetylation, phosphorylation, methylation, and ubiquitination.
Indeed, vimentin is a good substrate for numerous protein kinases (Eriksson et al., 2004; Izawa and Inagaki, 2006).
Tau is a substrate for numerous protein kinases and its hyperphosphorylation negatively regulates the stabilization of neuronal microtubules (Johnson and Stoothoff, 2004).
Multi-drug transporters have overlapping substrate specificity for numerous hydrophobic compounds and there seems to be considerable overlap in the efflux transporters used by certain anti-HIV drugs raising the possibility that inhibiting more than one transporter at a time may be one approach to improve CNS delivery of anti-HIV drugs.
The roles that nucleotides play in cellular metabolism range in scope from their use as enzyme substrates to regulators for numerous biochemical pathways.
The films were deposited using asymmetric bi-polar pulsed sputtering on a variety of substrates to allow for numerous analysis techniques.
Although we subsequently identified p21 as a novel in vitro substrate for RSKs, numerous experiments revealed that BI-D1870 mediathesehestressess responses via a yet unknown RSK-independent pathway.
The great number of dehydrogenases available makes the concept applicable for numerous substrates to analyse.
As shown for numerous substrates, these CTFs or NTFs may then be subject to further proteolytic processing (RIPping) by intramembrane-cleaving proteases (I-CLiPs) [ 78].
In the cardiomyocyte, ATP generated from substrate catabolism is used for numerous cellular processes including maintaining ionic homeostasis, cell repair, protein synthesis and turnover, organelle turnover, and contractile function.
However, while numerous substrates for the mammalian cell death-associated caspases have now been described, few caspase substrates have been identified in other organisms.
