Natto, therefore, contains numerous useful substrates for human health derived from the soybeans, B. subtilis, and soybean fermentation products.
Sugar is one of the most important substrates for human diet and it is an essential product of the human life.
The nido-carboranyl thymidine analogues were designed to be effective substrates for human thymidine kinase 1 in combination with an increased water solubility sufficient for clinical application in boron neutron capture therapy.
Recombinant Chinese hamster caspase-2 and -9 expressed in Escherichia coli show highest activities towards commercial peptide substrates Ac-VDVAD-pNA and Ac-LEHD-pNA, the designated commercial substrates for human caspase-2 and -9, respectively.
While numerous substrates for human and mouse caspases have now been identified [9], [10], it is not clear whether the same subset of proteins is targeted for proteolysis by caspases in other organisms.
This idea was proposed on the basis of the following considerations: First, some of the catechol-containing bioflavonoids and tea catechins are exceptionally good substrates for human COMT [11].
