Sentence examples for substrates both in from inspiring English sources

MAPKs have a large range of substrates both in the cytoplasm and in the nucleus, where they actively promote the transcription of new genes.

As for the B cells, N-terminal proteomics revealed a reduced N-terminal acetylation of classical/predicted NatA-type substrates, both in primary and hTERT-immortalized S37P fibroblasts (Fig.  7A E and Table  1; Supplementary Material, Tables S6 and S7).

We also demonstrate that this enzyme appears to function as an acyl-CoA desaturase that has preference for ω3 substrates both in planta and in yeast.

This article describes techniques that employ antisense and decoy oligodeoxynucleotides (ODN) to determine the roles of specific molecular substrates both in endogenous rhythmicity and in regulating the effects of light on the mammalian circadian clock.

Metal colloids have become the most commonly used substrates, both in SERS and in SEIRA, thanks to their easy preparation and the possibility of inducing aggregation, during and post synthesis [6],[7].

First, we examined conformational flexibility of the substrates both in water and bound to Mhp1 using molecular dynamics simulations (see Materials and Methods and Supplementary Methods).

Similar to PTP1B, TCPTP uses autophosphorylated IR as a direct substrate both in vivo and in vitro (Lammers et al., 1993; Galic et al., 2003).

The IP-IKK complex was analyzed in an in vitro kinase assay using a recombinant GST-IκBα protein as substrate both in the absence and in the presence of GlcN and NAPA.

Twinning faults are observed in Cu substrate both during the indentation and retraction processes.

Polyamines are substrates for transglutaminases both in vitro and in vivo [ 65].

Designed sensor comprising the IP3-binding core domain of IP3-receptor fused between complementary non-functional fragments of firefly luciferase allows direct detection of IP3 in presence of luciferin substrate both in cell lysate and in living cells.