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These viruses present fully dsRNA substrates as part of their genomes or as replication intermediates.
The ubiquitin family consists of a group of approximately 10 structurally related but functionally distinct proteins that are conjugated to substrates as part of regulatory signal transduction pathways.
Toeholds can also be exchanged on DNA substrates as part of a toehold-mediated strand displacement mechanism that allows facile equilibration of different nucleic acid species.
Activation of caspase-3 results in the degradation of a number of intracellular and cytoskeletal protein substrates as part of an ordered process of cellular disassembly, leading to apoptotic cell death (Mancini et al., 1998; Sun et al., 1999).
The F93 mutation was made to show that this residue interacts with real substrates as part of catalysis, supporting the claim that the structures visualize an active conformation and that the inhibitors are pseudo substrates.
Some lactate can also be exported to adjacent cells, tissues and organs to serve as oxidative or gluconeogenic substrates as part of an adjacent 'cell-to-cell lactate shuttle' [ 26].
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This results in a predictive controller that performs a pre-determined heating sequence prior to the arrival of the substrate as part of the resulting feedforward/feedback strategy to eliminate the load disturbance.
Firstly, it should be immobilized on an inorganic substrate as part of a longer-term project involving microreactor methods.
That unoccupied fresh food is apparently the least powerful reward appears plausible, because in a Petri dish assay digging into the substrate, as part of the larvae's attempts to find shelter, is easier if the food is softened by the past-presence or is cracked-up by the efforts of acutely present other larvae (or of any other agent of decay, we hesitate to add).
The reason why we choose these substrates as a part of our experiment is their possibility to fabricate linear or nonlinear optical devices for further applications.
It is unclear whether phosphorylation affects Pellino substrate specificity, as has been observed for E3 ubiquitin ligase Nedd4-2, in which phosphorylation of Nedd4-2 inhibitsubstratete binding as part of a regulatory mechanism for maintaining proper epithelial Na+ transport.
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