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This cellular phenotype may represent a potential substrate for developing therapeutic strategies through phenotypic suppression screenings.
3,3′-Diaminobenzidine (Sigma, St Louis, MO, USA) solution (0.4 mg ml−1, with 0.003% hydrogen peroxide) was used as a substrate for developing colour.
However, it is well known that the athlete's heart is characterized by increased LA size and left ventricular mass, adaptations that may create the substrate for developing AF.
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These two forms of porous silicon, macro and nano, are promising substrates for developing new 3-D cell culture platforms with applications in tissue engineering as well as basic cell biology research.
However, the uses of uniform nanostructured surfaces as SERS-active substrates for developing cell-based chips could be considered an excellent nondestructive bioanalytical tool for monitoring the efficiency of anticancer drugs and for the real-time studying of action mechanism of different anticancer drugs for both in vitro and in vivo studies.
Polystyrene microparticles with highly monodisperse size distributions were readily acquired commercially; this made them attractive substrates for developing new methods.
Yet another myth that can now be put to rest is that plenty of compost or other organic materials should be mixed with the soil from the planting hole to create a fluffy, rich substrate for the developing roots.
SuperSignal West Pico chemiluminescent substrate (Pierce) was used for developing blots.
Materials and process issues for passive elements such as resistors, capacitors, and inductors and the need for developing alternative substrate materials have also been addressed in this paper.
A novel method with high flexibility and efficiency for developing SERS substrates is proposed by patterning nanostructures on Si substrates using focused ion beam direct writing (FIBDW) technology following with precise thermal evaporation of gold film on the substrate.
This may provide access to a new lead for developing ERK1/2 substrate-specific inhibitors.
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