Sentence examples for substrate commitment from inspiring English sources

This assumption is consistent with the poor substrate commitment demonstrated by ISWI-containing chromatin remodelers for nucleosome repositioning.

The reconstituted system permitted quantitative mechanistic analysis to reveal key aspects of substrate discrimination and commitment for degradation.

However, the molecular mechanism underlying the substrate-dependent osteogenic commitment of these cells remains unclear.

First, members of both protein families are associated with the pre-mRNA substrate from the early commitment complex to the final active C complex (reviewed by Wang et al. 2006; Wahl et al. 2009), as depicted on the left side of the figure under splicing complexes.

We found that the stiffest substrates direct osteogenic lineage commitment of ASCs regardless of the presence or absence of growth factors, while softer substrates require biochemical cues to direct cell fate.

These findings point to potential engineering targets for improving yield and increasing oil contents by, respectively, reducing substrate cycling and increasing the commitment of plastidic carbon into fatty acid synthesis at the level of pyruvate kinase.

We obtain the differentiation towards tubular cells of ARPCs cultured in basal medium conditions, the tubular commitment thus being specifically induced by micropatterned substrates.

Forward commitment (Cf) is the probability for the substrate-enzyme complex to form products rather than return to free enzyme and substrate.

Reverse commitment is the probability of the enzyme bound products to form substrate rather than dissociating from the enzyme.

Aurora-A and its substrates complete the assignments in cell division coordinately through phosphorylation reactions, such as centrosome maturation, spindle assembly, mitotic commitment and cytokinesis [2].

We hypothesized that both substrate topographical and biochemical cues promote BM-HSCs adhesive behaviors, which are crucial for BM-HSCs' homing, self-renewal and lineage commitment within their microenvironment.