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In another study, participants performed a digit-symbol substitution task (DSST) designed to minimize WM storage capacity requirements and maximize processing speed requirements during fMRI scanning.
The testing battery included the following items: finger tapping, rapid alternating movements, verbal fluency, Rey Auditory Verbal Learning Task, digit symbol substitution task and simple and complex reaction times.
Measures of subjective sleepiness (Stanford Sleepiness Scale, Karolinska Sleepiness Scale and Visual Analogue Scale), objective sleepiness (sleep latency tests), objective performance (Symbol Digit Substitution Task) and reaction time (Psychomotor Vigilance Task) were taken before the night-nap (0230 h) and at several intervals post-nap.
As shown in Figure 1B, the 3 groups showed no differential changes on Digit Symbol Substitution Task [DSST; 28] performance across chronic PSD (day×genotype: F5.79, 365.01 = 1.55, p = 0.163) nor did scores change significantly across days (day: F2.90, 365.01 = 1.55, p = 0.163).
Psychomotor speed capacity was measured by the symbol substitution task.
Symbol search task and digit symbol substitution task (SST, DSS, German version of the WISC-IV).
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The WHO [ 65, 74] therefore calls for checks and balances, because health worker substitution, task-shifting and task-shifted models represent a radical departure from conventional delivery models that depend on specialist workers and should thus be implemented alongside other efforts to increase the numbers of skilled (professional) health workers.
However, health-worker substitution and task shifting in HIV care and ART delivery should not be seen as a panacea for all HRH challenges.
The machine learning problem can be specified as follows: given the amino acid sequence of a protein and a single amino acid substitution, the task is to predict whether the substitution may alter protein stability.
If the former is the primary focus of policy makers, they will need to focus on questions of substitution and task transfer, and fund nurses to take on work currently performed by doctors.
When properly implemented and managed, health-worker substitution and task shifting can indeed contribute in major ways towards improving and expanding coverage and access to HIV services, and towards ensuring sustainable, cost-effective, accessible and equitable health care [ 10, 66- 69].
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