Sentence examples for substitution sequence from inspiring English sources

One representative strategy is based on molecular design, in which amino acid substitution, sequence variation, terminal capping, molecular geometry, and amino acid chirality are considered.

Immunofluorescence confirmed that that both wild type Als5p (and5pWtheand the substitution sequence (Als5pV326N) were expressed on the yeast cell surface, with non-amyloid Als5pV326N expression slightly greater than Als5pWT (Figure 1B).

To predict the joint evolution of male and female phenotypes, we embedded our model into a trait substitution sequence process.

For the reference sequences (Roche 454 reads here), a SNP base quality score (≥ 30) and a neighbourhood quality standard (NQS) 11 base score (≥ 20) are applied which together can filter out over 70% of substitution sequence errors.

To predict the significance of the R406H substitution, sequence alignment of CHEK2 exon 10 was analyzed across ten species, revealing a modest conservation of the arginine residue amongst higher eukaryotes, with 6/10 species displaying homology (Table 3).

Taken together, we conclude that the obtained sequence error map is stable and sufficiently robust to discriminate substitution sequencing errors from low-level mosaicism.

Under the trait-substitution sequence limit, a phenotype that is convergent stable is also evolutionary stable (Wakano and Lehmann 2012).

Let d DCJ sb (P ) be the DCJ-substitution distance of P, that is the minimum cost of a DCJ-substitution sequence of operations sorting P separately.

The DCJ-substitution distance of genomes A and B, denoted by d DCJ sb (A, B ), is then the minimum cost of a DCJ-substitution sequence that sorts A into B. If w=1, this corresponds exactly to the minimum number of steps required to sort A into B and can be computed in linear time [ 8].

Since NEWBLER aligns reads allowing gaps instead of substitutions, sequence variant callers cannot identify SNPs and INDELs accurately.

For each IS group, sequences obtained from PCR fragments were aligned with Bioedit, and pairwise nucleotide divergence between each pair of sequences was calculated with MEGA ver 4.0 based on observed nucleotide substitutions (sequence alignments are available upon request).