Sentence examples for substitution number from inspiring English sources

It means that we have counted for each type of nucleotide the fraction of substituted (observed number) and used it for estimating the corrected substitution number according to Kimura's formula [ 31].

The mutant protein in strain CA4 has a lower substitution number which includes: I > V (232), P > S (245), M > V (246), and L > P (602).

The correlation between the PIPn criterion and the substitution number might suggest a neutral explanation (e.g. change in mutation pressure) of the variation in substitutional profile over time.

Particularly for closely related species, this substitution number must not be too small because the effect of sequencing errors on the determination of significantly conserved sequences may not be negligible.

Thus, we determined that a substitution number of two was the appropriate threshold for extraction of HCNSs of primates and rodents (P < 2.1 × 10−3 and P < 1.5 × 10−5, respectively, the binomial model).

The number of substitutions occurring at each site can be recorded during the simulation process and the observed α at a site equals the number of recorded substitutions at that site divided by the average substitution number for all sites.

Compensatory mutations may increase substitution numbers at paired sites.

Nucleotide substitution numbers, however, must be estimated using little-divergent sequences because of mutational saturation.

We then drew Poisson-distributed samples using these substitution numbers as the means.

I.e. unpaired sites with high numbers of optimal codons may experience reduced synonymous substitution numbers due to translational selection while paired sites with high numbers of non-optimal codons may experience reduced synonymous substitution numbers due to structural selection.

Ref. [ 3] analyzed the distribution of silent substitution numbers per silent site K s between pairs of recently duplicated genes.