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Structure activity relationship studies on these conjugates indicated that introduction of electron-withdrawing fluorine(s) on the phenyl ring in the PAB linker uniformly improved the chemical stability of the conjugates while the position of substitution affected differently the self-immolative process of conjugates upon proteolysis.
A non-synonymous substitution affected codon 768.
Thus, in a substrate-dependent manner the Phe217Leu substitution affected γ-secretase cleavage activity.
The R221C substitution affected ADAMTSL2 by leading to secretion of disulfide-bonded homodimers of mutant ADAMTSL2.
Although we have demonstrated the importance of single nucleotide substitution at M847 of Gn protein for wt RVFV mouse virulence, further studies are required to determine how this single nucleotide substitution affected RVFV's virulence.
The difference between inhibition of the wild-type RAD52 and RAD52Y104pCMF for ssDNA wrapping by dsDNA confirmed that Y104pCMF substitution affected dsDNA-binding activity of RAD52.
Similar(46)
However, lattice substitution affects only 5 10% of bone apatite [21].
So, substitution fails but not because the substitution affects the reference of the terms.
Indexed XRD patterns reveal Cu substitution affects the cell volume as compared with pristine spinel.
The substitution affects the oxygen vacancies which play an important role in determining the transport properties of YBCO.
Then substitution of co-referring singular terms within the scope of an attitude verb is blocked, as such substitution affects the semantic value of the attitude verb itself, but innocence is preserved.
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