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As their names imply, these variables impute (ie, substitute for) the unknown values of the variables of interest: E I substitutes for E 0, and D I substitutes for D 1.
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Presumably P-cadherin substitutes for E-cadherin to maintain cell-cell contacts, but not E-cadherin for P-cadherin.
Interestingly, the BAF complex cannot substitute for E-RC1 in β-globin gene expression, indicating that E-RC1 has a specialized function [ 80].
Since MDA-MB-231 and BT549-shLOXL2 cells maintain elevated levels of N-cadherin and cadherin11 (Fig 2G and Supporting Information Fig S4A), we speculate that either of those cadherins may substitute for E-cadherin in the maintenance of cell cell contacts and collaborate in the functional organization of tight junctions and cell polarity complexes in the absence of LOXL2.
In any case, K-cadherin alone cannot substitute for E-cadherin, as cell detachment from culture dishes was observed after prolonged YTX treatment of MCF-7 cells, when the cellular pool of K-cadherin was not disrupted yet To the best of our knowledge, this is the first report describing the expression of K-cadherin in breast cancer cells.
If we substitute Y for E, then H is called a tvs-H-cone metric (see [20]).
As a significant fraction of the metal cations may substitute for calcium (e.g., [43]), a iron-magnesium rich calcite may potentially form rather than ankerite and thereby reduce the amount of siderite formed.
Intracellular cell free extract from Lactobacillus spp. SBT2028 has been shown to be a suitable substitute for vitamin E deficiency and thereby reducing the oxidative stress in rats [71].
All the HIV items were retained for the CF scale, with the term 'CF' substituted for 'HIV' (e.g. "I have been hurt by how people reacted to learning I have HIV" to "I have been hurt by how people reacted to learning I have CF").
We can now substitute our expression for E in (equation 33) into equation 34 and make the further substitution that ε 1 = ε m and ε 2 = ε d corresponding to the permittivity of the metallic nanorod and dielectric host respectively.
These designs can be a good substitute for unknown E-optimal designs in some cases.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com