Sentence examples for substitute the essential from inspiring English sources

The ceasing of Global Fund support in China in 2013 will pose a threat to the development of integrated model because the local government in poorer provinces may not substitute the essential financial support.

Furthermore, animal proteins with similar domain organization such as human Tra2a and Trab cannot substitute for the essential splicing function of SR proteins [22].

Although this pathway does not substitute for the essential and more thoroughly studied Cdc13-Est1 telomerecruitmenttment pathway, the authors argue that this additional pathway may improve the robustness of the system for telomerase extension and provide additional means for its regulation.

Second, the use of null alleles distinguishes those human proteins that are truly substituting for the essential function of the yeast protein from those human proteins that are suppressing a growth phenotype by a secondary mechanism that may or may not relate to the conserved function.

Before starting to substitute the quasi-indirect approach of measuring change for the indirect approach in different applications, it is essential to understand these moderating factors.

"The interim relief is intended to provide a rough substitute for the essential service that municipal water systems must furnish: delivery of safe drinking water at the point of use," Lawson wrote in the 37-page order.

B. subtilis cells expressing only the FtsY-YFP fusion from the original gene locus were viable, indicating that FtsY-YFP was a functional substitute of the essential endogenous FtsY [ 29].

Substituting these essential metabolites into synthetic growth media might be one approach to successfully culturing those symbionts so far refractory to laboratory culture ex hospite.

Loss-of-function mutants of NbMAPKKKβ and NbMAPKKKγ were obtained by substituting methionine for the essential lysine in the ATP-binding site in the kinase domain.

Some divalent metal ions such as Cd2+ tend to substitute physiologically essential metal ions that act as enzyme cofactors or as structural constituents of proteins.

However, other metals, such as lead (Pb), mercury (Hg), and cadmium (Cd) may displace or substitute for essential trace metals and interfere with proper functioning of enzymes and associated cofactors.