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Hence, it is required a reliable and straightforward substitute methodology to assess splicing.
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Shibata and Sozen (1976) presented the substitute structure methodology for RC structures, and intended to devise a displacement based design method.
In the last decade, many approaches have been developed to complement or even substitute the current methodologies in cancer diagnosis and monitoring.
However, this methodology cannot substitute for direct real-life comparisons between these treatments.
This methodology cannot substitute for real-ife comparisons; however the present model represents a reasonable alternative approach and its assumptions are based on data from published studies in the literature and medical practice and are easy to handle.
This work employs the error propagation technique and Response Surface Methodology for substituting Monte Carlo simulations for library characterization.
PECp-lipase represents a faster, single step and, therefore, a very attractive substitute for the lipase standard methodology of pNP palmitate hydrolysis.
In this work we report the development of methodology to selectively substitute one of the two canonical fluorides common to most BODIPY dyes with alkoxy ligands, and show that the resulting dyes are highly soluble and cell permeable.
Analyses were done using both actual data collected and intent-to-treat methodology, based on substituting last acquired data for missing data.
While these are helpful, they are not really a substitute for further clarification of the methodology employed or validation of the procedures.
To accomplish this, a variable such as sucrose concentration could be substituted for pulse frequency, and the methodology introduced by Conover, Shizgal and Woodside [92] employed.
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