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The phrase "substitute a" is correct and can be used in written English.
It is commonly used when discussing replacement options or alternatives. Example: "I ran out of milk, so I had to substitute almond milk in my coffee this morning."
Exact(59)
Coaches may substitute a goalkeeper so long as play follows the regulations for player substitution.[16].[16]
In its place they seek to substitute a historical absolutism.
They decided to substitute a scene from daily life.
In most cases, pharmacists are allowed to substitute a generic for a brand-name drug.
Or substitute a sprinkling of cinnamon, nutmeg or ginger for an autumnal scent.
For "legitimacy" substitute a more familiar word that carries the same meaning in this context, authority.
McGuire persuaded a judge to substitute a QDOT.
According to its FAQ, pickers will "always" substitute a missing item with "the most suitable replacement".
Therefore the developed composites may substitute a standard PP-GF in some particular lightweight applications.
One would rather substitute a naturally variable residue than a conserved site.
One V atom is used to substitute a carbon in the diamond supercell with 144 atoms.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com