Sentence examples for substituent by from inspiring English sources

The dianion generated undergo an eletrophilic substituent by H+ ions, in a following chemical reaction.

Introduction of a terminal acidic group fixes the substituent by a salt-bridge to an Arg residue.

An ordered hexagonal mesophase was observed in both the unsubstituted glass (denoted in this paper as B: blank) and glasses containing <0.4% of substituent by X-ray diffraction, transmission electron microscopy and electron diffraction.

Two moieties of the 5-HT7/5-HT1A 5-HT7/5-HT1A 5-HT7/5-HT1Anyligandl]-1-(2-methoxyphenyl)piperazine (1) were linked through their 3-methoxy substituent by polymethylene chains of variable length, with the aim to increase the affinity for 5-HT7 receptor and the selectivity over 5-HT1A receptors.

The 1H and 13C NMR spectroscopic data of 1 (Table 2) was similar to those of geissoschizine methyl ether (4) [19] except methoxyl group in 4, substituent by -OH in 1, consistent with its molecular formula.

One possible source of this kinetic selectivity is that recognition of the fluorine substituent by FlK could force nucleophilic attack by Glu 50 to occur along a trajectory that is disfavored based on the Felkin Anh model for carbonyl addition.

In the present work we describe the synthesis and antiproliferative evaluation of a focused library of 30 novel oxazolidines designed by modification of N-substituent, by ring variation, by alkyl variation or by extension of the structure.

Optimization of substituents by parallel synthesis and the iterative design towards understanding structure activity relationship to improve potency are described.

Optimization of substituents by parallel synthesis and the iterative design toward understanding structure activity relationship to improve potency are described.

Replacement of the previously reported anilino substituents by benzylamino groups results in enhanced quadruplex interaction, and for one compound, superior telomerase inhibitory activity.

The relative efficacy of NO and OC bond homolysis was examined for alkoxyamines incorporating different R3 substituents by varying the potential difference applied to the collision cell, and comparing dissociation thresholds of each product ion channel.