Depending on the exposure, it can often be argued that the 000 effects are substantively most interesting, and easiest to interpret.
This increased processability was particularly interesting as E1 was substantively active during plant growth at ambient temperatures, however, after pretreatment processes (up to 170°C heat) E1 was not considered active in subsequent saccharification.
While the reviewers all find your work interesting, the revised manuscript does not substantively address all the four major concerns raised in the first review.
[Editors' note: further revisions were requested prior to acceptance, as described below.] While the reviewers all find your work interesting, the revised manuscript does not substantively address all the four major concerns raised in the first review.
The authors have indeed provided very interesting data for this issue, and have directly and substantively addressed the concern, improving the significance of the findings in the manuscript.
And substantively at times".
"Substantively, the bill is abysmal.
This makes little sense, substantively.
Ideologically and substantively, it is centrist.
It does – descriptively, substantively and symbolically.
