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The phrase "substantively greater" is correct and usable in written English.
It can be used to describe a difference or increase that is significant in nature or effect. Example: "The new policy resulted in substantively greater benefits for employees compared to the previous one."
Exact(8)
However, the difference in NA was substantively greater than that in EU.
In a practical sense, all of the disadvantages seemed to be substantively greater for women.
Descriptive diagnostics further supported this case, with the variance of the green space area variable (1.37e + 11 m2) substantively greater than the mean (455,061 m2).
We also found that the mean difference in fasting and postload glucose and fasting insulin relative to White British women was substantively greater when the woman and her partner were both born in South Asia.
Sequence nonidentities between the GPC of AV H0030026 and the GPC of the other North America arenaviruses (Table 2) were substantively greater than sequence nonidentities between the GPC of strains of phylogenetically closely related South American arenavirus species (3 ).
Bias towards publication of statistically significant results has been shown to be substantively greater for observational and laboratory-based studies than for randomised clinical trials (Easterbrook et al., 1991).
Similar(49)
Substantively, crime concentration is greater when fewer offenders account for a large proportion of crime.
"Substantively it was not his greatest speech.
"But substantively, it was not necessarily his greatest speech.
Engaging more substantively with local partners predeparture would provide greater scope for follow-up, map-based research, and advocacy to ensure that mapping projects address the needs and desires of the community.
Yet funds to substantively invest in restructuring the economy and address the greatest concentration of wealth since the Great Depression have not been forthcoming.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com