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Efficiency analyses can be substantively affected by the presence of outliers, which is why we tested the sensitivity of our results to outliers.
This process is guaranteed to monotonically converge on a mean estimate for the sample [11] and is not substantively affected by the initial choice of reference.
Although some studies found that psychological variables affect survival after bone marrow transplantation, the reviewers' analysis of the methodologically sound studies suggested that survival after bone marrow transplantation is not substantively affected by depressed mood or other psychopathology in adults or by social support in adults or children.
This does not mean, however, that local-scale interactions between predators and their prey are not substantively affected by emigration [52].
This similarity showed that all analyses were not substantively affected by missing data or differential rates of follow-up between trial arms.
In previous work on search strategy development in MEDLINE, we determined that estimation of search term performance was not substantively affected by using smaller journal subsets, focusing on journals publishing at least some methodologically rigorous articles [unpublished data], and these smaller subsets greatly simplify data processing.
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Fannie Mae and Freddie Mac (the GSEs), the dominant investors in subprime mortgage-backed securities before the 2008 crisis, substantively affected collateral composition in this market.
The decision curve was not substantively affected (data not shown).
Given that only about 5% of men would have received PSA screening during this time period, it is unlikely that any informal or opportunistic screening in Malmö could have substantively affected our estimates.
The overall conclusions were not substantively affected: the main effects of sample and clone were both still highly significant (P < 0.0001), and their interaction remained non-significant (P > 0.5).
NHS sites not covered by the MHRN differ in ways which substantively affect recruitment to trials.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com