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Professor David Petley, of the International Landslide Centre at Durham University, warns there is "substantive risk of an outburst" as the water level approaches the top of the dam, with "the potential for a large flood wave to travel downstream as far as Tarbela Dam", 50km northwest of Islamabad.
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"In a lot of car architectures, all the computers are interconnected, so that having taken over one component, there's a substantive risk that you could take over all the rest of them.
The study embraced the findings of the FDA and the EFSA, declaring that BPA posed no substantive risks.
Of major relevance is that the KAM appears to be amenable to change with non-surgical treatments such as shoes, gait modification strategies and braces by amounts that would correspond to a substantive reduction in risk of disease progression in knee OA [ 23- 26].
The risk of substantive effects occurring, however, is high.
We found substantive heterogeneity in the risk of psychological distress between and within ethnic groups.
The Regenstrief Institute (RI), Inc., contracted with the Indiana University Center for Bioethics (IUCB) to assess the RI component of their AHCIP and provide substantive, actionable recommendations to minimize the risk of potential or actual conflicts of interest and address other ethical issues.
There is large variation between practices in the extent that statins are prescribed to patients at high risk of CVD and a substantive number of patients at low risk of CVD.
Recently, a population-based case control study in Montreal found that workers with substantive exposure to asbestos had a greater risk of lung cancer, however, this finding did not achieve statistical significance (odds ratio (OR) =1.78, 95% CI=0.94, 3.36) [ 10].
More specifically, this paradigm change should allow for a substantive inclusion of risk reduction criteria and approaches in the Sustainable Development Goals that are to be adopted in New York in September 2015 and, more importantly due to its legally-binding nature, also will appear in the new agreement on climate change to be adopted in Paris in December 2015.
First, in household outbreaks susceptible individuals are at risk of infection via multiple modes, and substantive reductions in the risk of infection by one mode may not lead to overall reductions in the risk of infection.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com