Monitor says agency providers should not able to pay their staff more than the substantive rates for those NHS staff, with caps set at 55% above pay rates for each band or grade to cover expenses such as holiday pay, National Insurance contributions, "a nominal employer pension contribution and a modest agency fee".
Furthermore, when considering the substantive response rate seen in this trial, it appears that despite the use of a comparatively limited dose range of fluoxetine, patients were not under-dosed in this study.
Various studies, both retrospective and prospective, have shown that BEV with or without cytotoxic chemotherapy results in a substantive response rate and improved 6-month progression-free survival in GBM patients who have relapsed after previous RT/TMZ treatment [ 25].
Our major finding, substantive and increasing rates of MRSA in the outpatient setting, is particularly important as reports of MRSA acquired in the community increase across the country, and optimal strategies for the management of MRSA infections in the outpatient setting have yet to be established (14, 16, 25, 27– 30).
We reviewed other recent studies that examined tree pollen impacts on allergy and asthma outcomes, and found that, while direct comparisons are difficult because rate ratios are computed for different increments (e.g., inter-quartile-range), these studies also reported substantive impacts (e.g., rate ratios > 1.2 had they been computed per 0-to-98th percentile increase) [ 5, 9, 11].
Adjustment for a healthy population bias using this approach reduces the absolute difference in lung cancer mortality rates, but substantive trends remained by calendar year and birth cohort.
We encourage other investigators to similarly evaluate such item threshold in their research context because we have found this single decision to have substantive effects on participation rates.
There is insufficient high-quality information to meta-analyse or give substantive conclusions of the rate of clinical adverse events during out-of-hospital transport [ 49].
NCT00985673 In contrast to seasonal influenza outbreaks, high attack rates and substantive morbidity during the influenza A(H1N1 pdm09 pandemic appeared in young persons and adults under 65 years of age [ 1], and in subsequent analyses more than 75% of A(H1N1 pmd09-related H1N1 pmd09-relatedere estimatedeathsave occurred in these aged 18–64 years [ 2].
Weights have a substantive effect on overall MJH rates and, to a lesser extent, some of our other variables.
