Sentence examples for substantive impairment from inspiring English sources

Effects of diabetes on cardiac function were characterized, inter alia, by substantive impairment of functional indexes including LVEF, CO/LVM (a measure of myocardial efficiency [ 30, 33]), LVEDV/LVM, LVESV/LVM, stroke volume/LVM and elevated LVM/BW (the latter a measure of relative LV hypertrophy).

Trientine treatment significantly improved cardiac function in diabetic rats with substantive LV impairment.

Some authors proposed that it may be a good mortality predictor, 23, 24 and others associated it with a substantive quality of life impairment.

This gives substantive significance to DRL impairments because a functional consequence to impaired behavior can be demonstrated.

There is an increase in AUC and t1/2 for telavancin and a decrease in CL with increasing renal impairment, but no substantive change in maximum concentration after a single-dose administration.

Despite substantive research efforts, the mechanisms underlying cognitive impairment resulting from HIV infection are far from understood.

"Be substantive".

Impairment, maybe?

There are substantive issues.

It was substantive.

To be made substantive.