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In the way that they pursued knowledge and lived their lives, the Jameses had rejected the genteel tradition — "a sterile reverence for the past as past rather than a substantive connection to what's going on".
(During one surreal segment, in February, he tried to debate the merits of an anti-Trump protest with an actor from Los Angeles who had no substantive connection with the organizers).
"I absolutely never heard, smelled, saw or found any remote suggestion that there was some substantive connection, any connection, with organized crime," said Bob Woodward, the journalist and author who, with Carl Bernstein, did groundbreaking reporting on Watergate for The Washington Post in 1972.
The kinds of things we noted, the connection of things by the simultaneity rather than by their substantive connection is as common in business firms as it is in educational institutions.
Among many complaints about the film, reviewer Berge Garabedian derided the lack of much substantive connection to the Kubrick film (the latter of which he said was "funnier").
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Former bureau officials said that keeping even preliminary inquiries open past the point where they established substantive connections to security threats risked overtaxing law enforcement resources and missing genuine threats in the shuffle.
"[She] would appear to have significant mental health concerns … However it would appear that the only link to [this borough] is an address she stayed at for a little over 2 weeks and she has more substantive connections to services in the [another borough] area".
The possibility of substantive intellectual connections between aesthetics and evolutionary biology date back at least to Darwin's (1871) Descent of Man and Selection in Relation to Sex, in which he elaborated the theory of sexual selection by mate choice.
The standards addressed characteristics observed in student thinking and classroom interactions: higher-order thinking, depth of knowledge, substantive conversations, and connections to the world.
"This is especially upsetting because there are a number of political theorists and philosophers of color positioned to easily say something meaningful about the movement and its connection to substantive normative issues".
Indeed, the most substantive indication of a connection of NF-κB to human aging appears to be the prevalence of NF-κB target cytokines, such as IL-6, TNFα and IL-1, in serum.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com