Sentence examples for substantive challenges for from inspiring English sources

5 The total syntheses of 3′-aminoacyl and 3′-peptidyl-RNA represent substantive challenges for organic chemists; 2c, d therefore, a central focus of our research is the de novo synthesis of these derivatives.

This is particularly true for many long-lived species, such as conifers, but whose long generation times pose substantive challenges, including increased recalcitrance for SE as plants age.

Table  6 presents the recommendations from TDF-based map for the three most substantive challenges identified in this study, broken down into their underlying determinants.

They are home to some of his biggest political and substantive challenges, including a depressed economy, a disenchanted middle class and a disdain for government highlighted by the Tea Party movement.

"Substantive challenges remain".

Definitions, classification, and documentation are substantive challenges to comprehensive event capture.

The government's main problem, though, the substantive challenge, is the many complications associated with going there.

Probably the most substantive, challenging interview Barack Obama had in the election year was with the anchor of The Daily Show".

The most substantive challenge they appear willing to make toward the party's right-most wing is banalities about inflation.

Challenges for the Future.

Three Challenges For CIOs.