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Even though the evidence presented in this article is substantiated with a large number of case reports submitted from various settings with differing brand products, there remains no direct causation study that can make such a conclusive remark.
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However, our results need to be substantiated with an independent study with a large sample size.
Similarly, the facts stated between lines 39 and 45 need to be substantiated with a reference.
The signal hypothesis has been substantiated by a large body of experimental evidence.
We anticipate that these initial findings will likely be substantiated by a large-scale experiment with various types of viruses.
For BRCA2 mutation, an association with tubular/lobular carcinoma has been suggested, but not substantiated in a larger Breast Cancer Linkage Consortium study.
These results were substantiated in a larger study that employed 10 mice for each variant.
Whether our findings can be substantiated in a larger patient series has to be demonstrated in future trials.
This connection with allergy has been further substantiated with the association of a S100A7/psoriasin gene polymorphism with allergic rhinitis [ 33].
This point needs to be substantiated with further analysis to show an outcome-relevant specificity.
This theory is substantiated with much direct and indirect evidence.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com