Surgeons may have had concerns that delaying theatre may lead to an increased infection rate, but these results do not substantiate this concern.
An example to substantiate this concern is the last reported case of smallpox in a human, which originated from a laboratory (2 ).
However, Bourdette notes that research has not substantiated this claim.
The results of FGD substantiated this evidence.
Therefore, epidemiologic as well as mechanistic and therapeutic evidence substantiates the concern that TDCs may adversely affect cardiovascular risk in humans by reducing serum T4.
However, the authors also report notable off-target effects of CRISPR-based gene-editing, low efficiency of homologous recombination directed repair (HDR), mosacism and unwanted mutations, substantiating the concerns that the therapeutic application of these new techniques could have unpredictable safety risks.
1 3 However, the literature describing an increased rate of exercise injuries in older adults is limited in substantiating these concerns.
Despite these theoretical drawbacks of CGM and interstitial glucose assessments, little evidence exists to substantiate these concerns.
The three-dimensional structures of the catalytic domains of USP2, USP7, USP8, and USP14 have revealed striking structural conservation of their active site, thus substantiating the concerns that drug development may be difficult (Hu et al. 2002, 2005, Avvakumov et al. 2006, Renatus et al. 2006).
Mr. Sullivan discovered that researchers at Brown University, the University of Minnesota and elsewhere substantiated his concern.
