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On the basis of the presence of the N- and C-terminal motifs, sequence analysis suggests that HydG could coordinate two site-differentiated [4Fe 4S] clusters, and EPR spectral simulations substantiated this concept by showing that distinct axial signals were present in the photoreduced enzyme state when SAM was present (Table 2).
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In order to substantiate this concept, the expression of CB1R and CB2R was evaluated on cell surface by means of cytometric analysis and confocal microscopy.
Further research will be needed to substantiate this concept.
A few studies have suggested that radiolabelled anticancer agents may provide a unique means for personalized treatment planning in cancer patients [ 2], but more studies are needed to substantiate this concept.
To substantiate this design concept, we first document the energetic costs of the THI4 and THIC steps in the pathway and explain how cutting these costs could substantially increase crop biomass and grain yields.
We substantiated the concept of a direct functional role for the CREB and AhR transcription factors by the following novel findings: 1) both proteins are physically associated with the −219/+7 FSCN1 promoter region in fascin-positive SW480 human colon carcinoma cells; 2), as confirmed by qRT-PCR, these associations are not detectable in fascin-negative SW1222 human colon carcinoma cells.
Furthermore, B-cell activation of the TNF family (for example, by B-cell-activating factor (BAFF), also known as B-lymphocyte stimulator (BLyS), and a proliferation-inducing ligand (APRIL)) has further substantiated the concept of a notable role for B-cell cytokines in the pathogenesis of SS [ 17].
This substantiates the concept that TOR function is highly conserved and that upstream and downstream aspects of this pathway can be effectively studied using zebrafish.
However, Bourdette notes that research has not substantiated this claim.
The results of FGD substantiated this evidence.
This paper substantiates the concept of zoning the Arabian Gulf region based on the prevailing climate and topography.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com