Skinstage activation of parasite-specific Treg-based systemic immunosuppression provides a fundamentally new, experimentally widely substantiated, immunological rationale, and precise focus, for research and vaccination strategy leading to potentially accelerated malaria eradication.
With this series of papers, evaluators are being called to substantiate the rationale and warrant for their own evaluative actions in ways parallel to how evaluators question the logic of program interventions, both as designed and as implemented.
The chapter further ponders how the science of evolution of carbon in the universe would be pivotal for substantiating the rationale that life on Earth is not a localized phenomenon, but a marked legacy of the primeval cosmic carbon.
However, we would need to conduct further research to substantiate this rationale.
We speculate that this difference reflects how asymmetrical use of the upper limbs is more common than for the lower limbs, but further research is necessary to substantiate this hypothesized rationale for the differences noted.
However, regulatory authorities often require that a dietary supplement product be registered or licensed with documentation substantiating the safety, scientific rationale for claims, and quality specifications for the finished good and/or individual ingredients.
However, the rationale for choosing a particular human decision model is often not sufficiently empirically or theoretically substantiated in the model documentation.
However, the rationale for performing an OGTT in all patients with FPG < 110 mg/dL (6.1 mmol/L) was not substantiated and such practice may also entail testing a large number of patients, which may not be feasible.
No allegations were substantiated.
One complaint was substantiated.
Only one has been substantiated.
