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This was further substantiated in a recent paper, where the authors provided evidence that rhl system is able to overcome the absence of the las system by activating specific LasR-controlled functions, including production of 3-oxo-C(12 -HSL and PQS [12 -HSL
However, these effects are not substantiated in a recent meta-analysis of multiple trials with data available for HER2 and TOP2A [ 8].
This has been substantiated in a recent study (N.P.B., A.M. Farcas, T. Kondo, H.W. King, J.F. McGouran, L.L.P. Hanssen, S. Ito, S.C., K. Kondo, Y. Koseki, T. Ishikura, H.K. Long, T.W. Sheahan, N.B., B.M. Kessler, H.K., and R.K., unpublished data).
However, these findings were not substantiated in a recent case-control study examining 467 asthmatic patients and 288 unrelated healthy controls in a Chinese Han population, which showed an enrichment of Gc2-2 in asthma cases (OR = 1.35: CI = 1.01 1.78; p = 0.006) 116.
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This was substantiated in a follow-up study (15 ).
These results were substantiated in a larger study that employed 10 mice for each variant.
These findings have been substantiated in a number of other studies [ 3, 4].
However, this finding could not be substantiated in a later and more thoroughly performed study [ 19].
Early experience using pump therapy documented increased risk of diabetic ketoacidosis but this has not been substantiated in more recent trials and should be largely preventable by appropriate sick day rules training, a standard part of the DAFNE curriculum.
Furthermore, due to improved methodological approaches, causal relations have substantiated in recent years.
12 Genetic involvement has been substantiated in recent decades by the finding of several disease-causing genes and risk factors.
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