The assumption is not very well substantiated, however.
The effectiveness and benefits of regionalized trauma care are well substantiated; however, the effectiveness of regionalized burn care and potential benefits of burn center verification have not been fully validated.
Background: Concerns that Internet gambling has elevated the prevalence of problem gambling have not been substantiated; however, evidence suggests a subgroup of Internet gamblers do experience higher rates of gambling harms.
"There were some points that were accurate; there were two that we cannot substantiate, however.
It is important to emphasize that evidence for high molecular weight protein binding in the case of S100A6 was not substantiated conclusively, however antibody detection of S100A6 in solution did require addition of detergent (0.16% SDS) in raw serum in order to render the analyte available for antibody binding and to obtain optimal ECLISA signals.
The role of viruses – such as human papillomavirus (HPV) or human herpes virus (HHV) implicated in other oral malignancies – has not been substantiated [157 159]; however, a role for the human immunodeficiency virus (HIV) has been postulated [160,161] for anorectal mucosal melanomas.
A causative role of BAFF in cancer and cancer cachexia independent of inflammation has been difficult to substantiate; interestingly however, Koizumi et al. have shown that in vitro incubation of tumor cells isolated from pancreatic ductal adenocarcinoma (PDAC) patients with human recombinant BAFF resulted in altered phenotype with increased invasiveness and motility.
He substantiated his claim, however, by translating a number of documents, including a Hittite legal code, and publishing Hethitische Keilschrifttexte aus Boghazköi… (1919; "Hittite Cuneiform Inscriptions from Boǧazköy…").
Several reviews however, substantiated the safety of Cimicifuga racemosa preparations [64, 65].
Careful review of the paper, however, substantiated the journal's position that the paper lacked scientific merit.17 Other claims of prejudice against creationists and critics of evolution have surfaced over the years, including, for example, the case of Guillermo Gonzalez, an astrophysicist who was denied tenure allegedly for his allegiance to ID (Bergman 2008; Discovery Institute 2008).
The transgenic models for amyloid and tau pathology have not, however, substantiated this hypothesis to the fullest, although they have been invaluable for understanding molecular mechanisms of amyloid peptide generation, amyloid pathology, repercussions on cognition and behavior [13] [17].
