The appeal board of the industry's self-regulatory body, the Prescription Medicines Code of Practice Authority, ruled yesterday that Glaxo had committed three breaches of the code of practice that says information and claims about a drug must be based on evidence, "must not mislead directly or by implication", must be substantiated by clinical experience and should be presented in a balanced way.
This, however, is not substantiated by our experience with the 15D instrument in many other routine interventions studied in our sample [ 15].
The deleterious effects of eubaric hyperoxia (that is, adult respiratory distress syndrome, atelectasis, ventilation/perfusion mismatch) have been postulated, which may be due to concomitant pulmonary contusion, aspiration or even high ventilator pressures [ 12], but have not been substantiated by clinical experience [ 3- 5, 9].
The possibility that psychological pathways might contribute is also substantiated by recent experiences with Dutch food banks.
However, many of these instruments assess the risk for the recurrence of child maltreatment either among juveniles who experienced substantiated maltreatment or among juveniles who are already under the supervision of child protection services.
The Norwegian experience substantiates claims that effective public strategies should be firmly based upon long-term commitments, employ a combination of policies and measures conducive to technical change and innovation, and be capable of guarding against path dependence.
These premises are supported by research from the domains of behavioral economics, psychology, judgment and decision making, neuroeconomics, marketing, and engineering design, and are substantiated by the authors' own experience.
Additional limitations included the use of caregiver proxy interviews to substantiate children's experiences.
Cosmetic camouflage provides a significant emotional benefit for patients with facial skin conditions, and this is substantiated by a literature review and personal experience.
The observed rainfall association can be substantiated by the location of Rufiji where it experiences a tropical climate with a long rainy season from February to May and short a rainy season from October to December.
Compared to the low MDQ group, the high MDQ group experienced approximately twice as many intrusive images, substantiated by convergent measures.
