This bonding was not predicted in the deleterious background (Leu195-Ile196, Figure 1C), strongly indicating an impairment in protein folding, a hypothesis substantiated by functional evaluations of the affected patient [ 31].
Specifically, we propose a solution framework that is closer to being optimal than existing techniques are, which is substantiated in our evaluation study with real-world datasets.
The findings in the evaluation substantiated how this time interval was central to the positive effect of the online contact.
Therefore, ontology evaluation can be further substantiated by an application-based evaluation (see Figure 2).
Thereby, the potential of the proposed method is substantiated while a practical evaluation is aspect to future studies.
These hypotheses, if substantiated, imply that the initial evaluation of all existing and new biomarkers should be in negatively controlled heterogeneous randomised trials; otherwise, the surrogacy potential of these biomarkers may be underestimated.
Equations for additional margins of design lateral pressure coefficient and/or safety factors against sliding and overturning for the wall, expressed as a function of maximum foundation settlement, are proposed to substantiate the safety evaluation of soil retaining walls situated on a deformable foundation.
This study investigates the mechanisms by which a masonry vaulted structure responds to settlement of supports considering a wide range of possible settlement scenarios through a numerical model substantiated with experimental evidence and on-site evaluations.
Looking forward, the claims of conceptual mappings and their exploitation need to be substantiated and the processes validated, through illuminative evaluation studies.
But the aviation agency also said that on closer evaluation, 60 findings could not be substantiated and had been dropped.
We have substantiated the applicability of the proposed algorithm by an evaluation on a dataset of images from 132 normal subjects and 72 glaucoma patients.
