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However, such cut-offs are just technically substantiated to date, and there is a need to validate cut-off points prospectively to establish clinically relevant methylation thresholds.
Background: To date, no substantiated studies have been performed to investigate the efficacy of spinal manipulative therapy on thoracic spinal syndromes.
This month, the schools chancellor, Dennis M. Walcott, ordered a review of all substantiated cases of misconduct dating to 2000, pledging to remove any teachers who were found to have engaged in sexually inappropriate behavior.
Hoping to quell anxiety after three members of the teaching staff were arrested and accused of sexual crimes involving students, Dennis M. Walcott, New York City's schools chancellor, ordered a review of all substantiated cases of misconduct dating back to 2000 on Friday and pledged to remove any teachers who had engaged in sexually inappropriate behavior.
A book needs a more substantial and substantiated theme than this.
Documentation included tape recordings, photographs, sight records, auditory observations, and substantiated observations by recognized experts dating back to 1991.
In a statement (pdf), the IPCC said the paragraph "refers to poorly substantiated estimates of rate of recession and date for the disappearance of Himalayan glaciers.
However, to date there have been no previous substantiated reports of resting state correlations in the spinal cord.
Ford's story is mostly substantiated indirectly, but it does have substantiation.
VA Assistant Inspector General Linda Halliday said her office substantiated claims of data manipulation at a Philadelphia benefits office, saying processors changed dates for old benefits claims, making them appear new.
Of those, 41 were "not substantiated", 13 were still being investigated and five had been "partially substantiated on lesser matters".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com