The following pilot-tests (N = 5 CME executives) did not substantiate changes in content but resulted in minor refinements in the wording of some questions.
Though documented numerical increases in enrolment and female enrolment are not clearly substantiated, the changes in individual children, their families, their communities and their schools are well documented in the data collected.
We conclude that more compelling evidence and converging data from animal studies is required to substantiate structural changes in the adult human brain with training, especially in the neocortex.
Further research is required to substantiate that changes in transcript abundance in the current study were associated with alterations to enzyme activity.
To further substantiate the changes in topo I activity observed in mammospheres, we utilized other cancer stem cell systems.
They underwent standard examinations to substantiate inflammatory changes in the oral and nasal cavities, assessments of their lung function, airway responsiveness and atopic state.
The behavioural abnormalities linked to AD in the clinic have been substantiated by histological changes in the SCN in postmortem brains, in particular the cell loss observed by Swaab and colleagues (Swaab et al., 1985; Swaab et al., 1988).
To further substantiate the observed changes in single muscle groups, soleus muscles from some of the above animals were explanted and subjected to twitch and tetanic force recordings.
This confirms the conformational change substantiated in the X-ray structure of the substrate bound complex [10].
Recently, a pattern of chromosome regions showing up- or down- regulation of transcription in the trisomic genome based on RNAseq and substantiated with correlated regional changes in chromosome architecture was reported by Letourneau et al. (Letourneau et al., 2014).
