Sentence examples for substantiated by specific from inspiring English sources

Furthermore, the intake of coumarins, platelet aggregation inhibitors, or heparins was not substantiated by specific laboratory measures such as INR or thrombin time.

This explanation has been substantiated by specific canine experiments conducted by Niemann and coworkers [ 6] that subsequently tested the resuscitation effects of high-dose adrenaline administered before and after countershocks.

Secondly, this may be substantiated by specific histological findings in available tumors, such as triple negative breast cancers (BRCA1-associated), high grade papillary serous ovarian cancer (BRCA1- and 2-associated), endometrioid cancer of the uterus (MMR-gene-associated) and microsatellite instability (MMR-gene-associated).

Monophyly of the Cathaya– Pinus Picea subclade is strongly substantiated by a specific 4-nt insertion and an 18-nt deletion in the introns of trnA-UGC and trnG-UCC, respectively (fig. 5 B, indels 2 and 4; supplementary fig. 5, Supplementary Material online).

This hypothesis is also substantiated by the non-specific inhibition of adherence in the agarose-coated plates after 72 h of TPA treatment, whereby the amount of asCD11b cells remained at a similar level as compared to pMTH1 control transfectants which were unable to adhere to the agarose surface.

This intracellular distribution could be substantiated by recording the wavelength-specific intensity distribution of a cytoplasm-plasmalemma-cell wall section of neighbouring tobacco epidermal cells co-expressing GFP-AHK5 and the red fluorescent plasmalemma marker pm-rk-CD3-1007 (Fig. 1D; [27]).

Moreover, the phylogenetic origin of specific transcripts and corresponding expressed functions was further substantiated by a global read-coverage of specific genes, such as genes that are highly expressed by dominant microbial members of the ecosystem.

This is substantiated by the fact that ketoconazole, a specific inhibitor of CYP3A4, is an excellent inhibitor of 3-hydroxycarbofuran formation in HLM (IC50: 0.31 μM).

Monophyly is substantiated by the presence of a cluster specific subsequence between Cys45 and Cys52 that was identified earlier (Abad-Zapatero et al. 1996) (fig. 5 A).

Purity of subcellular fractions was further substantiated by means of immunological methods using the specific organelle marker antigens clathrin (plasma membrane) (1∶250 dilution) and lamin A/C (nuclei) (1∶100 dilution).

Furthermore, this prominent and specific infiltration could be substantiated by immunohistochemical analyses that demonstrated a strong peri- and intra-tumoral infiltration of MHC class II-expressing host's cells surrounding virally-infected cancer cells.