Accordingly, the variables, categories and assessment criteria substantiated by the previous concept exploration are summarized in Table 3 in Appendix.
The resulting conformationally constrained PNA is utilized for the synthesis of PNA mixmers and the concept is substantiated by UV-Tm studies of the resulting PNA2 DNA complexes.
The CLOUD-HSPCs concept was substantiated by in vitro data from cell culture; therefore, to confirm the CLOUD-PSPCs model, the planarian community needs to develop new tools, like live cell tracking.
This concept is substantiated by recent studies that map anatomical pathways, or which demonstrate that hormones and neurotransmitters associated with energy homeostasis regulation can directly modulate reward and motivation behaviors.
This concept is substantiated by the finding that a gradient of expression of galectin-3, a well-know molecule associated to thyrocytes transformation, has been observed in different clusters of morphologically categorised HTs.
The concept proposed is substantiated by wide simulation of the machine dynamics.
This concept has been substantiated by a number of experimental and clinical studies, which have used antimicrobial (silver coated) endotracheal tubes to inhibit biofilm formation [33]-[36] [33]-[36]olonisation of the aireduce33]-[36] and decolonisationncidence of VAP [37].
This dislocation engineering concept has been successfully substantiated by the design and fabrication of a deformed and partitioned (D&P) steel with a yield strength of 2.2 GPa and an uniform elongation of 16%.
This concept has been further substantiated by recent studies in infants and young children with CF who were diagnosed by newborn screening and followed longitudinally by annual chest computed tomography (CT) and bronchoalveolar lavage (BAL) [49, 50].
Considering these criticisms and the point that the glymphatic concept represents a fundamental revision of the current understanding of CSF physiology, we feel that the concept needs to be substantiated by comprehensive ultrastructural investigations.
Broad notes that this is substantiated by the fact that a cat or a dog that lacked concepts might, it seems, have a prehension of something as red even though it cannot (lacking the requisite concepts) literally know or judge that it is red.
