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The model is substantiated using experimental data from several published studies.
The ancestral results were further explained and substantiated using New Hampshire census data from 1870 to 1930 when the largest waves of European immigrants came to the area.
Future studies should integrate behavioral designs and should use additional psychophysiological measures (e.g., eye-tracking) in order to substantiate this interpretation.
A-domain specificities were also substantiated using phylogenetic analysis (Additional file 3: Figure S2).
Notably, the interaction of position 268 with the TCR (A268D) was further substantiated using A268V6 and A268N6 as additional APLs (data not shown).
This observation was further substantiated using PCA and hierarchical clustering (Additional file 3), where samples primarily clustered by tissue.
Functional connectivity in each group was substantiated using cross-subject correlations between mean activations within regions isolated via the imaging data analysis.
The study intends to contribute additional data to further substantiate the critical need for interventional research on this topic, and to identify which specific characteristics of alcohol use are associated with unsafe sex and violence.
Therefore, additional data are needed to substantiate the possibility that smoke exposure alters alveolar epithelial cell function and predisposes cells to additional injury.
The biochemical characterization of the encoded T. urticae CAS/CYS enzyme also appears to be solid, although some additional data are requested to substantiate conclusions of product formation and enzyme kinetic properties (please see below).
With the additional data we reconfirmed and substantiated a differential risk of venous thromboembolism between users of combined oral contraceptives with different progestogens and (although to a less extent) with different oestrogen doses.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com