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The SILAC data is presented in the current manuscript to substantiate the point that most proteins accumulate in the membrane in the absence of AP2, but GPI-linked proteins behave differently and therefore their sorting behaviour requires further study.
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We have made these corrections, as well as substantially revised the manuscript for clarity, in addition to the inclusion of new data to further substantiate the most important points of the paper.
To further substantiate this point, we studied the effect of dibromobimane (DBB, mass 350.01), a reagent known to cross-link cysteine residues within 3 6 Å distance [25].
More work should be performed to substantiate this point by adding the following experiments: - Experiments in Figure 8 show that Atl contributes to S. aureus virulence but they do not show if this is linked to a higher activation of the Toll pathway.
To substantiate this point, Figure 3 highlights the high similarity of SF and orientation spectra of stimulus images before and after phase scrambling.
12.01pm: Here's what Carol Day, WWF-UK's solicitor, had to say: The Red Tape Challenge suggests that the Habitats Directive Regulations were a 'burden on business', but when we asked Defra we were told that the review had no submissions to substantiate that point and found no evidence of delays to decision-making or gold-plating.
The concept of threshold approach in clinical decision-making has existed since the 1970s, and this concept has been substantiated to the point that ignoring it would be unethical [ 24- 26].
Examples of national trends taken from a large collated, spatially explicit dataset [16, D. Sumilo 2006, DPhil thesis, Oxford University], to be published separately, substantiate this point (Fig. 8).
To further substantiate this point, we perform a series of permutations towards disease-disease, domain-disease, and domain-domain relationships.
To substantiate the original data we have now included additional time points during gene induction.
Such a separation is necessary to substantiate the two steps of the two part model from an economic point of view.
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