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We took a conservative approach to substantiate the identified A5E events, by realigning all corresponding transcripts to the same genomic sequence with two other algorithms, EXALIN and BLAT (the latter lacks an explicit splice site model).
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This conclusion was further substantiated by the varying contribution of the identified QTL regions to the genotypic variance.
To further substantiate our findings, we investigated the expression levels of target proteins of the identified metastamiRs.
While the identified variations at 1q43 represent a potential risk locus for UL, future replication studies are required to substantiate our observation.
While the identified variations at 1q43 represent a potential risk locus for UL, future replication analyses are required to substantiate our observation.
In order to substantiate that the variation identified is causal to CNDI in the family and investigate the underlying mechanism responsible, we further investigated the cellular handling of the AQP2 protein in Madin-Darby canine kidney (MDCK) cells stably expressing AQP2-R254W.
31 Related stories, statements, words and phrases related to participants' beliefs about CLBP were coded into common themes in NVivo and a back and forth process between data undertaken to substantiate or challenge identified themes.
The objectives of this retrospective cohort study were to substantiate the status and to identify disease-specific, functional and infrastructural factors associated with the hospital mortality, in order to produce evidence for upgrading health care.
Can a mutually exclusive categorization scheme be proposed, which would be conceptually sound and empirically substantiated? 2) Do the categories identified in response to our first research question have specific determinants?
In comparisons with mechanistic powder compaction models, measurements of particle deformation, contact areas, and coordination numbers were found to substantiate the importance of the experimentally identified mechanisms.
To substantiate the genomic data and further identify proteins contributing to the apoptotic resistance phenotype, B-SWCNT and B-Control cell protein lysates were subjected to a human apoptosis protein expression array (see Additional file 1: Table S1 for array layout) in duplicate following manufacturer's instructions (R & D Systems, Minneapolis, MN, USA).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com