They showed that the army had substantiated more than 300 claims of massacre, murder, rape and torture by American soldiers.
Mass spectrometric quantification confirmed a major reduction in total 5mC and also in 5-hydroxymethylcytosine. Bisulfite sequencing (BS-seq) at 8.8× genome coverage substantiated more than 50% loss of CpG methylation genome wide, along with lower non-CpG methylation.
Nonetheless, it might be felt that unless Stroud can substantiate his more principled objection to the very possibility of crossing the 'bridge of necessity' that is required by any sort of world-directed transcendental claim, he has still not yet established conclusively that no transcendental argument can be made to work, and must always either fall short or end up being superfluous.
Note, however, that PRO instruments that measure a simple concept may not be adequate to substantiate a more complex claim.
In particular, this case study captured perceived benefits, so further work can provide evidence to substantiate and more precisely document these improvements.
With respect to particular parameters, the results obtained with the Erasmus Ladder can be comparable to those of other tests, but its precise quantification of a wide range of parameters can still reveal additional phenotypes that are hard to substantiate with more classic methods (e.g., Galliano et al. 2013a, b).
If his results are substantiated in more rigorous follow-up research, I will be greatly concerned.
Part of the motivation is based on the fact that existing studies on the value attributes of hybrid offerings are mostly conceptual and need to be further substantiated through more systematic empirical studies.
Some fixed point theorems for contractive-type mappings in cone metric spaces have been substantiated; for more details, see [16 25].
"Gossip" might come into it, but – usually juicy and negative – gossip STAYS gossip unless it can be substantiated but more than one, preferably two sources AND it passes a public interest test.
